*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TF5775000
CHEMICAL NAME           : Phosphorothioic acid, O,O-diethyl O-pyrazinyl ester
CAS REGISTRY NUMBER     : 297-97-2
BEILSTEIN REFERENCE NO. : 0884916
REFERENCE               : 5-23-11-00128 (Beilstein Handbook Reference)
LAST UPDATED            : 199706
DATA ITEMS CITED        : 12
MOLECULAR FORMULA       : C8-H13-N2-O3-P-S
MOLECULAR WEIGHT        : 248.26
WISWESSER LINE NOTATION : T6N DNJ BOPS&O2&O2
COMPOUND DESCRIPTOR     : Agricultural Chemical
SYNONYMS/TRADE NAMES :
   * AC 18133
   * American cyanamid 18133
   * CL 18133
   * Cynem
   * Cynophos
   * O,O-Diaethyl-O-(pyrazin-2-yl)-monothiophosphat
   * O,O-Diaethyl-O-(2-pyrazinyl)-thionophosphat
   * O,O-Diethyl O,2-pyrazinyl phosphorothioate
   * Diethyl O-2-pyrazinyl phosphorothionate
   * O,O-Diethyl O-2-pyrazinyl phosphorothionate
   * O,O-Diethyl O-pyrazinyl thiophosphate
   * EN 18133
   * ENT 25,580
   * Ethyl pyrazinyl phosphorothioate
   * Experimental nematocide 18,133
   * Nemafos
   * Nemaphos
   * Nematocide GR
   * Phosphorothioic acid, O,O-diethyl O-2-pyrazinyl ester
   * Pyrazinol, O-ester with O,O-diethyl phosphorothioate
   * RCRA waste number P040
   * Thionazin
   * Thionazine
   * Zinofos
   * Zinophos
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   14,515,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SPEADM Special Publication of the Entomological Society of America.  (4603
   Calvert Rd., College Park, MD 20740)  Volume(issue)/page/year: 78-1,46,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JDAH "Organophosphorus Pesticides: Organic and Biological Chemistry," Eto,
   M., Cleveland, OH, CRC Press, Inc.,  1974  Volume(issue)/page/year:
   -,197,1974
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Ocular
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GYAV "Pflanzenschutz-und Schaedlingsbekaempfungsmittel: Abriss einer
   Toxikologie und Therapie von Vergiftungen," 2nd ed., Klimmer, O.R.,
   Hattingen, Fed. Rep. Ger., Hundt-Verlag, 1971  Volume(issue)/page/year:
   -,36,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,498,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - pigeon
DOSE/DURATION           : 2370 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ASTTA8 ASTM Special Technical Publication.  (American Soc. for Testing
   Materials, 1916 Race St., Philadelphia, PA 19103)  No.1-    1911-
   Volume(issue)/page/year: (680),157,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : 3160 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ASTTA8 ASTM Special Technical Publication.  (American Soc. for Testing
   Materials, 1916 Race St., Philadelphia, PA 19103)  No.1-    1911-
   Volume(issue)/page/year: (680),157,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - duck
DOSE/DURATION           : 1680 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   47,451,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Bird - duck
DOSE/DURATION           : 7 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   47,451,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 2420 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ASTTA8 ASTM Special Technical Publication.  (American Soc. for Testing
   Materials, 1916 Race St., Philadelphia, PA 19103)  No.1-    1911-
   Volume(issue)/page/year: (680),157,1979

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   On EPA IRIS database

 
                            *** END OF RECORD ***