*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TG0400000
CHEMICAL NAME           : Phosphorothioic acid, O,S-dimethyl
                          O-(4-nitro-m-tolyl) ester
CAS REGISTRY NUMBER     : 3344-14-7
BEILSTEIN REFERENCE NO. : 2386675
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C9-H12-N-O5-P-S
MOLECULAR WEIGHT        : 277.25
WISWESSER LINE NOTATION : WNR B1 DOPO&S1&O1
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * O,S-Dimethyl-O-(3-methyl-4-nitrofenyl)thiofosfat
   * 8062 HC
   * Isosumithion
   * Metathion, S-methyl isomer
   * S-Methyl fenitrooxon
   * S-Methyl fenitrothion
   * Phosphorothioic acid, O,S-dimethyl O-(3-methyl-4-nitrophenyl) ester
   * Sumithion S-isomer
   * Thiophosphate de O,S-dimethyl et de O-(3-methyl-4-nitrophenyle)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 315 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - bronchiolar constriction
   Gastrointestinal - changes in structure or function of salivary glands
   Endocrine - other changes
REFERENCE :
   PCBPBS Pesticide Biochemistry and Physiology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1971-  Volume(issue)/page/year:
   6,280,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 320 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - bronchiolar constriction
   Gastrointestinal - changes in structure or function of salivary glands
   Endocrine - other changes
REFERENCE :
   PCBPBS Pesticide Biochemistry and Physiology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1971-  Volume(issue)/page/year:
   6,280,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 54 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NNGADV Nippon Noyaku Gakkaishi.  Journal of the Pesticide Science Society of
   Japan.  (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170,
   Japan)  V.1-    1976-  Volume(issue)/page/year: 3,35,1978
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Dominant lethal test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 1 mg/kg
REFERENCE :
   PCBPBS Pesticide Biochemistry and Physiology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1971-  Volume(issue)/page/year:
   6,280,1976
 
                            *** END OF RECORD ***