*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TG1650000 CHEMICAL NAME : Phosphorothioic acid, O-(2-(ethylthio)ethyl) O,O-dimethyl ester CAS REGISTRY NUMBER : 867-27-6 BEILSTEIN REFERENCE NO. : 1707378 REFERENCE : 4-01-00-02445 (Beilstein Handbook Reference) LAST UPDATED : 199707 DATA ITEMS CITED : 9 MOLECULAR FORMULA : C6-H15-O3-P-S2 MOLECULAR WEIGHT : 230.30 WISWESSER LINE NOTATION : 2S2OPS&O1&O1 COMPOUND DESCRIPTOR : Agricultural Chemical SYNONYMS/TRADE NAMES : * Demeton-O-methyl * Demeton-O-metile * O,O-Dimethyl-O-(2-aethylthio-aethyl)monothiophosphat * O,O-Dimethyl 2-ethylmercaptoethyl thiophosphate, thiono isomer * O,O-Dimethyl-O-(2-ethyl-thio-ethyl)-monothiofosfaat * O,O-Dimethyl O-ethylmercaptoethyl thiophosphate * O,O-Dimethyl O-2-(ethylthio)ethyl phosphorothioate * O,O-Dimetil-O-(2-etiltio-etil)-monotiofosfato * Ethanol, 2-(ethylthio)-, O-ester with O,O-dimethyl phosphorothioate * beta-Ethylmercaptoethyl dimethyl thionophosphate * O-(2-(Ethylthio)ethyl) O,O-dimethyl phosphorothioate * 2-(Ethylthio)ethyl dimethyl phosphorothionate * Methyl-demeton-O * O-Methyldemeton * Thiophosphate de O,O-dimethyle et de O-2-ethylthio-ethyle *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 75 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 22,559,1959 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 216 mg/kg TOXIC EFFECTS : Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation REFERENCE : BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 67,187,1957 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 46 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 22,559,1959 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 30 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 22,559,1959 TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 20 mg/m3 TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 28(3),21,1963 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 75 mg/kg TOXIC EFFECTS : Behavioral - tremor REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 22,559,1959 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 46,1,1973 TOXICOLOGY REVIEW MZUZA8 Meditsinskii Zhurnal Uzbekistana. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1957- Volume(issue)/page/year: (8),90,1973 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-DENMARK:TWA 0.05 ppm (0.5 mg/m3);Skin JAN 1993 *** END OF RECORD ***