*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TH8575000 CHEMICAL NAME : Phthalanilic acid, 4'-(2-thiazolylsulfamoyl)- CAS REGISTRY NUMBER : 85-73-4 LAST UPDATED : 199701 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C17-H13-N3-O5-S2 MOLECULAR WEIGHT : 403.45 WISWESSER LINE NOTATION : T5N CSJ BMSWR DMVR BVQ COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * AFI-Ftalyl * (o-Carboxybenzoyl)-p-aminophenylsulfonamidothiazole * Cremothalidine * Enteramida * Entero-sulfina * Entexidin * Entexidina * Ftalazol * Ftalylsulfathiazol * Intestiazol * Phthalazol * Phthalazole * Phthaloylsulfathiazole * 2-(N(sup 4)-Phthalyaminobenzenesulfonamide)thiazole * 2-(N(sup 4)-Phthalyaminobenzenesulfonamido)thiazole * 2-(p-Phthalylaminobenzenesulfamido)thiazole * Phthalylnorsulfazole * 2-(N(sup 4)-Phthalylsulfanilamido)thiazole * 2-(p-N-Phthalylsulfanilyl)aminothiazole * Phthalylsulfathiazole * Phthalylsulfonazole * Phthalylsulphathiazole * Sulfacetil * Sulfanilamide, N(sup 4)-(o-carboxybenzoyl)-N'-2-thiazolyl- * Sulfaphthalazole * Sulfathalidine * Sulftalyl * Taleudron * Talidine * Taloudron * Thalazole * Thalistanin * Thalistatyl * 4'-(2-Thiazolylsulfamoyl)phthalanilic acid * 4'-(2-Thiazolylsulfamyl)phthalanilic acid * Ultratiazol *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(12),9,1993 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 81,116,1944 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 920 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 81,116,1944 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 12900 mg/kg/30D-I TOXIC EFFECTS : Gastrointestinal - changes in structure or function of esophagus REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 58(12),9,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84641 No. of Facilities: 193 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 9471 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84641 No. of Facilities: 16 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 94 (estimated) No. of Female Employees: 62 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***