*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TH8750000
CHEMICAL NAME           : Phthalanilic acid, 4'-(2-thiazolylsulfamoyl)-, sodium
                          salt
CAS REGISTRY NUMBER     : 63868-70-2
LAST UPDATED            : 199607
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H12-N3-O5-S2.Na
MOLECULAR WEIGHT        : 425.43
WISWESSER LINE NOTATION : T5N CSJ BMSWR DMVR BVQ &-NA-
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-(N(sup 4)-Phthalylsulfanilamido)thiazole sodium salt
   * Phthalylsulfathiazole, sodium salt
   * Sodium phthalylsulfathiazole
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 81,116,1944
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 6 gm/kg/6D-I
TOXIC EFFECTS :
   Liver - other changes
   Kidney, Ureter, Bladder - other changes
   Related to Chronic Data - death
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 81,116,1944
 
                            *** END OF RECORD ***