*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TI1270000 CHEMICAL NAME : Phthalic acid, diisodecyl ester CAS REGISTRY NUMBER : 26761-40-0 BEILSTEIN REFERENCE NO. : 2171889 LAST UPDATED : 199806 DATA ITEMS CITED : 15 MOLECULAR FORMULA : C28-H46-O4 MOLECULAR WEIGHT : 446.74 COMPOUND DESCRIPTOR : Reproductive Effector SYNONYMS/TRADE NAMES : * 1,2-Benzenedicarboxylic acid, diisodecyl ester * Bis(isodecyl)phthalate * DIDP (plasticizer) * Diisodecyl phthalate * Palatinol Z * Sicol 184 * Vestinol DZ *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 64 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 3,131,1973 TYPE OF TEST : LC - Lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >130 mg/m3/6H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EXXON* Exxon Chemical Company. (P.O. Box 3272, Houston, Texas 77001) TYPE OF TEST : LC - Lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >130 mg/m3/6H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EXXON* Exxon Chemical Company. (P.O. Box 3272, Houston, Texas 77001) TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 22500 uL/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 3,61,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >3160 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EXXON* Exxon Chemical Company. (P.O. Box 3272, Houston, Texas 77001) TYPE OF TEST : LC - Lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : >130 mg/m3/6H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EXXON* Exxon Chemical Company. (P.O. Box 3272, Houston, Texas 77001) ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 58800 mg/kg/14W-C TOXIC EFFECTS : Liver - changes in liver weight REFERENCE : EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 3,131,1973 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 10 gm/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 35,501,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-SWEDEN:TWA 3 mg/m3;STEL 5 mg/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83278 No. of Facilities: 1017 (estimated) No. of Industries: 18 No. of Occupations: 41 No. of Employees: 21856 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83278 No. of Facilities: 2962 (estimated) No. of Industries: 53 No. of Occupations: 57 No. of Employees: 80441 (estimated) No. of Female Employees: 31734 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY EPA TSCA Section 8(d) unpublished health/safety studies EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998 *** END OF RECORD ***