*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TJ2360000 CHEMICAL NAME : Physostigmine, methiodide CAS REGISTRY NUMBER : 6091-11-8 LAST UPDATED : 199009 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C15-H21-N3-O2.C-H3-I MOLECULAR WEIGHT : 417.33 WISWESSER LINE NOTATION : T B556 EN GNTT&J B1 E1 G1 KOVM1 &I1 SYNONYMS/TRADE NAMES : * AR-45 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 43,413,1931 TYPE OF TEST : LD80 - Lethal Dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 750 ug/kg TOXIC EFFECTS : Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - coma Lungs, Thorax, or Respiration - respiratory stimulation REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB158-508 *** END OF RECORD ***