*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TJ4200000 CHEMICAL NAME : Picolinaldehyde, thiosemicarbazone CAS REGISTRY NUMBER : 3608-75-1 BEILSTEIN REFERENCE NO. : 0132695 REFERENCE : 5-21-07-00311 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C7-H8-N4-S MOLECULAR WEIGHT : 180.25 WISWESSER LINE NOTATION : T6NJ B1UNMYZUS COMPOUND DESCRIPTOR : Drug Mutagen SYNONYMS/TRADE NAMES : * 2-Formylpyridine thiosemicarbazone * Hydrazinecarbothioamide, 2-(2-pyridinylmethylene)- * NSC 729 * Picoline-2-aldehyde thiosemicarbazone * 2-Pyridinecarboxaldehyde thiosemicarbazone * Pyridine-2-carboxaldehyde, thiosemicarbazone *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 70 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,676,1965 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 30910 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986 ** MUTATION DATA ** TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 2500 umol/L REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 21,3213,1972 *** END OF RECORD ***