*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TJ4200000
CHEMICAL NAME           : Picolinaldehyde, thiosemicarbazone
CAS REGISTRY NUMBER     : 3608-75-1
BEILSTEIN REFERENCE NO. : 0132695
REFERENCE               : 5-21-07-00311 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C7-H8-N4-S
MOLECULAR WEIGHT        : 180.25
WISWESSER LINE NOTATION : T6NJ B1UNMYZUS
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 2-Formylpyridine thiosemicarbazone
   * Hydrazinecarbothioamide, 2-(2-pyridinylmethylene)-
   * NSC 729
   * Picoline-2-aldehyde thiosemicarbazone
   * 2-Pyridinecarboxaldehyde thiosemicarbazone
   * Pyridine-2-carboxaldehyde, thiosemicarbazone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 70 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 8,676,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 30910 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCISP* National Cancer Institute Screening Program Data Summary,
   Developmental Therapeutics Program. (Bethesda, MD 20205)
   Volume(issue)/page/year: JAN1986
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 2500 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   21,3213,1972
 
                            *** END OF RECORD ***