*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TJ7542000
CHEMICAL NAME           : Picolinic acid, 5-(4-chlorobutyl)-
CAS REGISTRY NUMBER     : 41135-83-5
BEILSTEIN REFERENCE NO. : 0473594
REFERENCE               : 5-22-02-00387 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H12-Cl-N-O2
MOLECULAR WEIGHT        : 213.68
WISWESSER LINE NOTATION : T6NJ BVQ E4G
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-(4-Chlorbutyl)picolinsaeure
   * 5-(4-Chlorobutyl)picolinic acid
   * 5-(4'-Chlorobutyl)picolinic acid
   * 5-(4-Chlorobutyl)-2-pyridinecarboxylic acid
   * FD 008
   * 2-Pyridinecarboxylic acid, 5-(4-chlorobutyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 470 mg/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 25,55,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 44 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #0066242
 
                            *** END OF RECORD ***