*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : TK6020200
CHEMICAL NAME : Pipecolanilide, 2',6'-dimethyl-1-(2-hydroxyethyl)-,
hydrochloride
LAST UPDATED : 198806
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C16-H24-N2-O2.Cl-H
MOLECULAR WEIGHT : 312.88
WISWESSER LINE NOTATION : T6NTJ A2Q BVMR B1 F1 &GH
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* AL-S-1249 hydrochloride
* 2',6'-Dimethyl-1-(2-hydroxyethyl)pipecolanilide hydrochloride
* Droxicainide hydrochloride
* Droxicainid hydrochlorid
* DL-N-(2-Hydroxyethyl)pipecolinyl-2,6-dimethylanilide hydrochloride
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 149 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 33,706,1983
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 280 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 33,706,1983
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 57 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 33,706,1983
*** END OF RECORD ***