*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TK7801380
CHEMICAL NAME           : 1-Piperazineacetamide, N-cyclohexyl-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 91290-76-5
LAST UPDATED            : 199406
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C12-H23-N3-O.Cl-H
MOLECULAR WEIGHT        : 261.84
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * CO 1063
   * N-((N-Cyclohexylcarbamoyl)methyl)piperazine hydrochloride
   * N-Cyclohexyl-1-piperazineacetamide monohydrochloride
   * Esaprazole hydrochloride
   * Hexaprazol hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   11,263,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 285 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   11,263,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 285 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   11,263,1986
 
                            *** END OF RECORD ***