*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TK7850000 CHEMICAL NAME : 1-Piperazineacetamide, N-isopropyl-4-(3,4,5-trimethoxycinnamoyl)-, maleate CAS REGISTRY NUMBER : 26328-00-7 LAST UPDATED : 198706 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C21-H31-N3-O5.C4-H4-O4 MOLECULAR WEIGHT : 521.63 WISWESSER LINE NOTATION : T6N DNTJ AV1U1R CO1 DO1 EO1& D1VMY1&1 &QV1U1QV -C COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * N-Isopropyl-4-(3,4,5-trimethoxycinnamoyl)-1-piperazineacetamide maleate * Maleate de cinpropazide * 68111 M.D. * (3',4',5'-Trimethoxycinnamoyl)-1-(N-isopropyl amino carbonyl methyl)-4 piperazine maleate *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1295 mg/kg TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - excitement REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 29,233,1974 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 450 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 4,293,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 475 mg/kg TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - excitement REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 29,233,1974 *** END OF RECORD ***