*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TK7862500
CHEMICAL NAME           : 1-Piperazineacetic acid,
                          4-(6-acetamido-3-nitro-2-pyridyl)-, ethyl ester
LAST UPDATED            : 198803
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H19-N5-O5
MOLECULAR WEIGHT        : 337.38
SYNONYMS/TRADE NAMES :
   * 4-(6-Acetamido-3-nitro-2-pyridyl)-1-piperazineacetic acid ethyl ester
   * 1-(6-Acetylamino-3-nitro-2-pyridyl)-4-ethoxycarbonylpiperazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2834 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 33,825,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2640 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 33,825,1987
 
                            *** END OF RECORD ***