*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : TK7906500
CHEMICAL NAME : 1-Piperazineacetic acid, 4-methyl-, mesityl ester,
dihydrochloride
CAS REGISTRY NUMBER : 2173-46-8
LAST UPDATED : 198209
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C16-H24-N2-O2.2Cl-H
MOLECULAR WEIGHT : 349.34
WISWESSER LINE NOTATION : T6N DNTJ A1VOR B1 D1 F1& D1 &GH 2
COMPOUND DESCRIPTOR : Drug
Primary Irritant
SYNONYMS/TRADE NAMES :
* FC 658
* 4-Methyl-1-piperazineacetic acid mesityl ester dihydrochloride
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 200 mg
REACTION SEVERITY : Moderate
REFERENCE :
BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica,
Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year:
107,310,1968
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1 gm
REACTION SEVERITY : Moderate
REFERENCE :
BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica,
Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year:
107,310,1968
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica,
Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year:
107,310,1968
*** END OF RECORD ***