*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TK7922850
CHEMICAL NAME           : Piperazine, 4-(1-adamantylmethyl)-1-cyclooctyl-
CAS REGISTRY NUMBER     : 101975-82-0
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C23-H42-N2
MOLECULAR WEIGHT        : 346.67
WISWESSER LINE NOTATION : L66 B6/B-H/DI A B- C 1B ITJ B1- AT6N DNTJ D- AL8TJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N'-(1-Adamantylmethyl)-N-cyclooctylpiperazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 105 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
   Behavioral - changes in motor activity (specific assay)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 12,772,1978
 
                            *** END OF RECORD ***