*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TK8220100 CHEMICAL NAME : Piperazine, 1-(1,3-benzodioxol-5-ylmethyl)-4-((4-chlorophenoxy)ac etyl)-, monohydrochloride CAS REGISTRY NUMBER : 34161-23-4 LAST UPDATED : 199009 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C20-H21-Cl-N2-O4.Cl-H MOLECULAR WEIGHT : 425.34 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Attentil * 1-(1,3-Benzodioxol-5-ylmethyl)-4-((4-chlorophenoxy)acetyl)piperazine hydrochloride * BP 662 * Fipexide hydrochloride * Fipexidum hydrochloride * Piperazine, 1-((p-chlorophenoxy)acetyl)-4-piperonyl-, monohydrochloride * Vigilor *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4482 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia REFERENCE : ACTTDZ Acta Therapeutica. (Pl. de Bastogne 8, B13, 1080 Brussels, Belgium) V.1- 1975- Volume(issue)/page/year: 11,387,1985 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 450 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia REFERENCE : ACTTDZ Acta Therapeutica. (Pl. de Bastogne 8, B13, 1080 Brussels, Belgium) V.1- 1975- Volume(issue)/page/year: 11,387,1985 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4150 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia REFERENCE : ACTTDZ Acta Therapeutica. (Pl. de Bastogne 8, B13, 1080 Brussels, Belgium) V.1- 1975- Volume(issue)/page/year: 11,387,1985 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 499 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - ataxia REFERENCE : ACTTDZ Acta Therapeutica. (Pl. de Bastogne 8, B13, 1080 Brussels, Belgium) V.1- 1975- Volume(issue)/page/year: 11,387,1985 *** END OF RECORD ***