*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TK8720000 CHEMICAL NAME : Piperazine, 1,4-bis(bis(1-aziridinyl)phosphinothioyl)- CAS REGISTRY NUMBER : 1950-08-9 BEILSTEIN REFERENCE NO. : 0629376 REFERENCE : 5-23-03-00231 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C12-H24-N6-P2-S2 MOLECULAR WEIGHT : 378.48 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 1,4-Bis(bis(1-aziridinyl)phosphinothioyl)piperazine * Phosphine sulfide, 1,4-piperazinediylbis(bis(1-aziridinyl)- * Thiodipine *** HEALTH HAZARD DATA *** ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2 gm/kg/10D-I TOXIC EFFECTS : Endocrine - changes in spleen weight Endocrine - changes in thymus weight Related to Chronic Data - death REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 24,732,1961 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1 gm/kg/10D-I TOXIC EFFECTS : Blood - leukopenia Related to Chronic Data - death REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 24,732,1961 *** END OF RECORD ***