*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TK9800000
CHEMICAL NAME           : Piperazine, 1,4-bis(alpha-methylphenethyl)-,
                          dihydrochloride
CAS REGISTRY NUMBER     : 13754-23-9
LAST UPDATED            : 199012
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C22-H30-N2.2Cl-H
MOLECULAR WEIGHT        : 395.46
WISWESSER LINE NOTATION : T6N DNTJ AY1&1R& DY1&1R &GH 2
SYNONYMS/TRADE NAMES :
   * N,N'-Bis(phenylisopropyl)piperazine, dihydrochloride
   * Bis-N,N'-(3-phenylpropyl-2)-piperazine dihydrochloride
   * Diphenazine, dihydrochloride
   * F 200
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 230 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 7,225,1957
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 193 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,223,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 7,225,1957
 
                            *** END OF RECORD ***