*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL1351800
CHEMICAL NAME           : 1-Piperazinecarboxylic acid,
                          4-(chlorodibenz(b,f)oxepin-10-yl)-, ethyl ester
CAS REGISTRY NUMBER     : 56958-66-8
LAST UPDATED            : 199106
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H21-Cl-N2-O3
MOLECULAR WEIGHT        : 384.89
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-(Chlorodibenz(b,f)oxepin-10-yl)-1-piperazinecarboxylic acid ethyl ester
   * Ethyl 4-(chlorodibenz(b,f)oxepin-10-yl)-1-piperazinecarboxylate
   * RMI 61392
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 25,1261,1975
 
                            *** END OF RECORD ***