*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TK8115000
CHEMICAL NAME           : Piperazine, 1-(3-amino-2-pyridyl)-4-(p-tolyl)-
CAS REGISTRY NUMBER     : 16019-80-0
BEILSTEIN REFERENCE NO. : 0620875
REFERENCE               : 5-23-03-00095 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H20-N4
MOLECULAR WEIGHT        : 268.40
WISWESSER LINE NOTATION : T6N DNTJ AR D1& D- BT6NJ CZ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(3-Amino-2-pyridyl)-4-(p-tolyl)piperazine
   * 4-(p-Tolyl)-1-(3-amino-2-pyridyl)piperazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,812,1967
 
                            *** END OF RECORD ***