*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL2816000
CHEMICAL NAME           : Piperazine, 1-(o-chlorophenyl)-4-nicotinoylmethyl-
CAS REGISTRY NUMBER     : 58013-13-1
LAST UPDATED            : 199307
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H18-Cl-N3-O
MOLECULAR WEIGHT        : 315.83
WISWESSER LINE NOTATION : T6N DNTJ AR BG& D1V- CT6NJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ketone, 4-(o-chlorophenyl)-1-piperazinylmethyl 3-pyridyl-
   * 1-(2-Keto-2-(3'-pyridyl)ethyl)-4-(2'-chlorophenyl)piperazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - central sympatholytic
   Vascular - BP lowering not characterized in autonomic section
   Lungs, Thorax, or Respiration - bronchiolar dilation
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   119,608,1980
 
                            *** END OF RECORD ***