*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL3856100
CHEMICAL NAME           : Piperazine,
                          1-(7,8-difluorodibenzo(b,f)thiepin-10-yl)-4-methyl-,
                          monomethanesulfonate
CAS REGISTRY NUMBER     : 60811-11-2
LAST UPDATED            : 198703
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H18-F2-N2-S.C-H4-O3-S
MOLECULAR WEIGHT        : 440.56
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(7,8-Difluorodibenzo(b,f)thiepin-10-yl)-4-methylpiperazine  
   methanesulfonate
   * 7,8-Difluoro-10-(4-methylpiperazino)dibenzo(b,f)thiepin methanesulfonate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 301 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - paresthesis
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 41,881,1976
 
                            *** END OF RECORD ***