*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL4235000
CHEMICAL NAME           : Piperazine,
                          1-(10,11-dihydro-8-ethoxy-3-fluorodibenzo(b,f)thiepin
                          -10-yl)-4-methyl-, (Z)-2-butenedioate (1:1)
CAS REGISTRY NUMBER     : 70931-67-8
LAST UPDATED            : 199606
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H25-F-N2-O-S.C4-H4-O4
MOLECULAR WEIGHT        : 488.62
WISWESSER LINE NOTATION : T C676 BS&T&J EF J- AT6N DNTJ D1& MO2 &QV1U1VQ -C
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Compound 12354
   *   2-Ethoxy-7-fluoro-11-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiep
     in maleate
   *   8-Ethoxy-3-fluoro-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiep
     in maleate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 91 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4243805
 
                            *** END OF RECORD ***