*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL4270000
CHEMICAL NAME           : Piperazine,
                          1-(10,11-dihydro-2-methyldibenzo(b,f)thiepin-10-yl)-4
                          -methyl-, (Z)-2-butenedioate,hydrate (2:2:1)
CAS REGISTRY NUMBER     : 73129-61-0
LAST UPDATED            : 198612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H24-N2-S.C4-H4-O4.1/2H2-O
MOLECULAR WEIGHT        : 449.56
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Methyl-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepin maleate 
    hemihydrate
   * VUFB13.752
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 333 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 44,2677,1979
 
                            *** END OF RECORD ***