*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL4280000
CHEMICAL NAME           : Piperazine,
                          1-(10,11-dihydro-8-methyldibenzo(b,f)thiepin-10-yl)-4
                          -methyl-, maleate (1:2)
CAS REGISTRY NUMBER     : 16174-71-3
LAST UPDATED            : 198612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H24-N2-S.2C4-H4-O4
MOLECULAR WEIGHT        : 556.68
WISWESSER LINE NOTATION : T C676 BS&T&J F1 I- AT6N DNTJ D1 &QV1U1VQ -C
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Dibenzo(b,f)thiepin, 10,11-dihydro-8-methyl-10-(4-methylpiperazino)-,  
   hydrogen maleate
   * 1-(10,11-Dihydro-8-methyldibenzo(b,f)thiepin-10-yl)-4-methylpiperazine  
   maleate (1:2)
   * Meperathiepin dimaleate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 93 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 33,1895,1968
 
                            *** END OF RECORD ***