*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TL4325000 CHEMICAL NAME : Piperazine, 1-(10,11-dihydro-8-methylthiodibenzo(b,f)thiepin-10-y l)-4-methyl-, maleate (1:1) CAS REGISTRY NUMBER : 19728-88-2 LAST UPDATED : 198706 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C20-H24-N2-S2.C4-H4-O4 MOLECULAR WEIGHT : 472.66 WISWESSER LINE NOTATION : T C676 BS&T&J FS1 I- AT6N DNTJ D1 &QV1U1VQ -C COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Dibenzo(b,f)thiepin, 10,11-dihydro-8-methylthio-10-(4-methylpiperazino)-, hydrogen maleate * Dibenzo(b,f)thiepin, 10,11-dihydro-10-(4-methylpiperazino)-8-methylthio-, hydrogen maleate * 1-(10,11-Dihydro-8-(methylthio)dibenzo(b,f)thiepin-10-yl)-4-methylpipera zine maleate * Methiothepin maleate * 8-Methylthio-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepin maleate * Metitepin maleate *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 125 mg/kg TOXIC EFFECTS : Behavioral - ataxia REFERENCE : CCCCAK Collection of Czechoslovak Chemical Communications. (Academic Press Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK) V.1- 1929- Volume(issue)/page/year: 39,3338,1974 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 67600 ug/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : CCCCAK Collection of Czechoslovak Chemical Communications. (Academic Press Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK) V.1- 1929- Volume(issue)/page/year: 39,3153,1974 *** END OF RECORD ***