*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL6455000
CHEMICAL NAME           : Piperazine,
                          1-(2-(2-(diphenylmethoxy)ethoxy)ethyl)-2,4,5-trimethy
                          l-, dihydrochloride, (E)-
CAS REGISTRY NUMBER     : 10140-09-7
LAST UPDATED            : 197904
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C24-H34-N2-O2.2Cl-H
MOLECULAR WEIGHT        : 455.52
WISWESSER LINE NOTATION : T6N DNTJ A2O2OYR&R& B1 D1 E1 &GH 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * trans-1-(2-(2-(Diphenylmethoxy)ethoxy)ethyl)-2,4,5-trimethylpiperazine  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 16,1557,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 16,1557,1966
 
                            *** END OF RECORD ***