*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL7000000
CHEMICAL NAME           : 1-Piperazineethanol,
                          4-(3-(2-chlorodibenz(b,e)oxepin-11(6H)-ylidene)propyl
                          )-, dihydrochloride, (Z)-
CAS REGISTRY NUMBER     : 14008-46-9
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C23-H27-Cl-N2-O2.2Cl-H
MOLECULAR WEIGHT        : 471.89
WISWESSER LINE NOTATION : T C676 BY IO JHJ EG BU3- AT6N DNTJ D2Q &GH
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * P 5227
   * Pinoxepin hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 7 mg/kg/D
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   CTCEA9 Current Therapeutic Research, Clinical & Experimental.  (Therapeutic
   Research Press, Inc., POB 514, Tenafly, NJ 07670)  V.1-    1959-
   Volume(issue)/page/year: 8,465,1966
 
                            *** END OF RECORD ***