*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TL7000000 CHEMICAL NAME : 1-Piperazineethanol, 4-(3-(2-chlorodibenz(b,e)oxepin-11(6H)-ylidene)propyl )-, dihydrochloride, (Z)- CAS REGISTRY NUMBER : 14008-46-9 LAST UPDATED : 198910 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C23-H27-Cl-N2-O2.2Cl-H MOLECULAR WEIGHT : 471.89 WISWESSER LINE NOTATION : T C676 BY IO JHJ EG BU3- AT6N DNTJ D2Q &GH COMPOUND DESCRIPTOR : Drug Human SYNONYMS/TRADE NAMES : * P 5227 * Pinoxepin hydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human DOSE/DURATION : 7 mg/kg/D TOXIC EFFECTS : Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy) REFERENCE : CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 8,465,1966 *** END OF RECORD ***