*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL7024400
CHEMICAL NAME           : 1-Piperazineethanol,
                          4-(7-chloro-10,11-dihydro-8-fluorodibenzo(b,f)thiepin
                          -10-yl)-, (Z)-2-butenedioate (1:1)
CAS REGISTRY NUMBER     : 60810-90-4
LAST UPDATED            : 198703
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H22-Cl-F-N2-O-S.C4-H4-O4
MOLECULAR WEIGHT        : 509.03
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   4-(7-Chloro-10,11-dihydro-8-fluorodibenzo(b,f)thiepin-10-yl)-1-piperazin
     eethanol maleate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 842 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - paresthesis
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle contraction or spasticity
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 41,881,1976
 
                            *** END OF RECORD ***