*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TL9900000 CHEMICAL NAME : 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)thioxanthen-9-ylidene)propyl )- CAS REGISTRY NUMBER : 2709-56-0 LAST UPDATED : 199507 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C23-H25-F3-N2-O-S MOLECULAR WEIGHT : 434.56 WISWESSER LINE NOTATION : T C666 BS IYJ IU3- AT6N DNTJ D2Q COMPOUND DESCRIPTOR : Drug Human SYNONYMS/TRADE NAMES : * Emergil * Fluanxol * Flupenthixol * (alpha,beta)-Flupenthixol * Flupenthixole * Flupentixol * Fluxanxol * LC 44 * N 7009 * 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)- * Siplaril * Siplarol * 2-Trifluoromethyl-9-(3-(4-(beta-hydroxyethyl)-1-piperazinyl)propylidene) thioxanthene * 4-(3-(2-(Trifluoromethyl)thioxanthen-9-ylidene)propyl)-1-piperazineethan ol * 4-(3-(2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)-1-piperazinee thanol *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - child DOSE/DURATION : 900 ug/kg TOXIC EFFECTS : Behavioral - sleep Behavioral - changes in motor activity (specific assay) Behavioral - coma REFERENCE : DICPBB Drug Intelligence and Clinical Pharmacy. (POB 42435, Cincinnati, OH 45242) V.3- 1969- Volume(issue)/page/year: 15,388,1981 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human DOSE/DURATION : 367 ug/kg/12D-I TOXIC EFFECTS : Behavioral - wakefulness Behavioral - muscle weakness Behavioral - headache REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 22,93,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,2121,1977 *** END OF RECORD ***