*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM0808500
CHEMICAL NAME           : 1-Piperazineethanol,
                          4-(1,5,b-trimethyl-1H-imidazo(4,5-b)pyrazin-2-yl)-
CAS REGISTRY NUMBER     : 55635-74-0
BEILSTEIN REFERENCE NO. : 1146205
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H22-N6-O
MOLECULAR WEIGHT        : 290.42
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2-(4-Hydroxyethylpiperazin-1-yl)-1,5,6-trimethyl-1H-imidazo(4,5-b)pyrazi
     ne
   * 1H-Imidazo(4,5-b)pyrazine,  
   2-(4-hydroxyethylpiperazin-1-yl)-1,5,6-trimethyl-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 655 mg/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 9,149,1975
 
                            *** END OF RECORD ***