*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM0845600
CHEMICAL NAME           : Piperazine,
                          1-(2-furanylcarbonyl)-4-(4-((4-(2-hydroxy-3-((1-methy
                          lethyl)amino)propoxy) phenyl)
                          amino)-6,7-dimethoxy-2-quinazolinyl)-,
                          trihydrochloride, dihydrate
CAS REGISTRY NUMBER     : 111218-85-0
LAST UPDATED            : 198903
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C31-H38-N6-O6.3Cl-H.2H2-O
MOLECULAR WEIGHT        : 734.15
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 38 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 21,478,1987
 
                            *** END OF RECORD ***