*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM0858500
CHEMICAL NAME           : Piperazine, 1-isonicotinoyl-4-(2-quinolyl)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 101153-54-2
LAST UPDATED            : 198712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H18-N4-O.Cl-H
MOLECULAR WEIGHT        : 354.87
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-Isonicotinoyl-4-(2-quinolyl)piperazine monohydrochloride
   * Piperazine, 1-(4-pyridinylcarbonyl)-4-(2-quinolinyl)-, monohydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 143 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
   Behavioral - muscle contraction or spasticity
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 49,7,1986
 
                            *** END OF RECORD ***