*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TL9390000
CHEMICAL NAME           : 1-Piperazineethanol,
                          4-(2-(o-methylsulfonylphenyl)imidazo(1,2-a)pyrimidin-
                          3-yl)methyl-
CAS REGISTRY NUMBER     : 3458-58-0
LAST UPDATED            : 199009
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H25-N5-O3-S
MOLECULAR WEIGHT        : 415.56
WISWESSER LINE NOTATION : T56 AN DN FNJ CR BSW&1& B1- AT6N DNTJ D2Q
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   Imidazo(1,2-a)pyrimidine,3-(4(2-hydroxyethyl)piperazinylmethyl)-2-(o-met
     hylsulfonylphenyl)-
   *   2-(o-Methylsulfonylphenyl)-3-(4-hydroxyethyl-1-piperazinylmethyl)imidazo
     (1,2-a)pyrimidine
   *   4-(2-(o-Methylsulfonylphenyl)imidazo(1,2-a)pyrimidin-3-yl)methyl-1-piper
     azineethanol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle contraction or spasticity
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 9,29,1966
 
                            *** END OF RECORD ***