*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM1776280
CHEMICAL NAME           : Piperazine,
                          1-(2-(4-methyl-2-(methylthio)-5-thiazolyl)ethyl)-4-(2
                          -methylphenyl)-, hydrochloride, hydrate (1:3:2)
CAS REGISTRY NUMBER     : 89663-36-5
LAST UPDATED            : 198712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H25-N3-S2.3Cl-H.2H2-O
MOLECULAR WEIGHT        : 490.98
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1-(2-(4-Methyl-2-(methylthio)-5-thiazolyl)ethyl)-4-(2-methylphenyl)piper
     azine 3HCl dihydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 415 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - tremor
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 40,159,1983
 
                            *** END OF RECORD ***