*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM1925000
CHEMICAL NAME           : Piperazine,
                          1-methyl-4-(3,3,3-tris(p-chlorophenyl)propionyl)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 1949-07-1
LAST UPDATED            : 199109
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C26-H25-Cl3-N2-O.Cl-H
MOLECULAR WEIGHT        : 524.34
WISWESSER LINE NOTATION : T6N DNTJ AV1XR DG&R DG&R DG& D1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Dicroden
   * Hetolin
   * LZ 544
   * 1-Methyl-4-(3,3,3-tris(p-chlorophenyl)propionyl)piperazine  
   monohydrochloride
   * 1-(beta,beta,beta-Tris(p-chlorophenyl)propionyl)-4-methylpiperazine  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 610 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals",
   11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year:
   11,739,1989
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAZMAE Fortschritte der Arzneimittelforschung.  Progress in Drug Research.
   (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way,
   Secaucus, NJ 07094)  V.1-    1959-  Volume(issue)/page/year: 17,108,1973
 
                            *** END OF RECORD ***