*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM2486800
CHEMICAL NAME           : Piperazine,
                          1-(2-oxo-2-(1-pyrrolidinyl)ethyl)-4-(1-oxo-3-(3,4,5-t
                          rimethoxyphenyl)-2-pr openyl)-
CAS REGISTRY NUMBER     : 23887-46-9
BEILSTEIN REFERENCE NO. : 0903854
REFERENCE               : 5-23-02-00271 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H31-N3-O5
MOLECULAR WEIGHT        : 417.56
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Cinepazide
   * Piperazine,  
   1-((1-pyrrolidinylcarbonyl)methyl)-4-(3,4,5-trimethoxycinnamoyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 44640 mg/kg/31D-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - proteinuria
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Related to Chronic Data - death
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 13,375,1979
 
                            *** END OF RECORD ***