*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM2490000
CHEMICAL NAME           : Piperazine,
                          1,1'-oxybis(dimethylsilylene)bis(trimethylene)bis(4-m
                          ethyl-, tetrahydrochloride
CAS REGISTRY NUMBER     : 84584-53-2
LAST UPDATED            : 199803
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H46-N4-O-Si2.4Cl-H
MOLECULAR WEIGHT        : 560.72
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,1'-Oxybis(dimethylsilylene)bis(trimethylene)bis(4-methylpiperazine)  
   tetrahydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 215 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - beta-adrenergic blockage
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 16,761,1982
 
                            *** END OF RECORD ***