*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM2676100
CHEMICAL NAME           : 1-Piperazinepropanol,
                          4-(6-((6-methoxy-8-quinolyl)amino)hexyl)-alpha-methyl
                          -, maleate (1:2)
LAST UPDATED            : 199509
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H38-N4-O2.2C4-H4-O4
MOLECULAR WEIGHT        : 646.82
WISWESSER LINE NOTATION : T66 BNJ HO1 JM6- AT6N DNTJ D2YQ1 &QV1U1VQ 2
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 8-(6-(4-(3-Hydroxybutyl)piperazin-1-ylhexyl)amino)-6-methoxyquinoline  
   di(hydrogen maleate)
   * 4-(6-((6-Methoxy-8-quinolyl)amino)hexyl)-alpha-1-piperazinepropanol  
   maleate
   * Moxipraquine di(hydrogen maleate)
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 90 mg/kg
SEX/DURATION            : female 8-16 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
   Reproductive - Specific Developmental Abnormalities - homeostasis
REFERENCE :
   TRSTAZ Transactions of the Royal Society of Tropical Medicine and Hygiene.
   (Royal Soc. of Tropical Medicine and Hygiene, Manson House, 26 Portland Pl.,
   London W1N 4EY, UK)  V.14-    1920-  Volume(issue)/page/year: 74,43,1980
 
                            *** END OF RECORD ***