*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM2786200
CHEMICAL NAME           : Piperazine,
                          1-(2-(2-(alpha-(o-tolyl)benzyloxy)ethoxy)ethyl)-2,4,5
                          -trimethyl-, dihydrochloride, (E)-
CAS REGISTRY NUMBER     : 74038-16-7
LAST UPDATED            : 197904
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H36-N2-O2.2Cl-H
MOLECULAR WEIGHT        : 469.55
WISWESSER LINE NOTATION : T6N DNTJ A2O2OYR&R B1& B1 D1 E1
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 85 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 16,1557,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 16,1557,1966
 
                            *** END OF RECORD ***