*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM2900000
CHEMICAL NAME           : Piperazine,
                          1-(4-((7-(trifluoromethyl)-4-quinolinyl)amino)benzoyl
                          )-
CAS REGISTRY NUMBER     : 72141-43-6
BEILSTEIN REFERENCE NO. : 6244849
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H19-F3-N4-O
MOLECULAR WEIGHT        : 400.44
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(4-((7-(Trifluoromethyl)-4-quinolinyl)amino)benzoyl)piperazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1778 mg/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 29,133,1986
 
                            *** END OF RECORD ***