*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM3000000
CHEMICAL NAME           : Piperazinium, 1,4-bis(2-chloroethyl)-1,4-dimethyl-,
                          dichloride
CAS REGISTRY NUMBER     : 63867-58-3
LAST UPDATED            : 198603
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H22-Cl2-N2.2Cl
MOLECULAR WEIGHT        : 312.14
WISWESSER LINE NOTATION : T6K DKTJ A2G A1 D2G D1 &Q 2 &G 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N,N'-Dimethyl-N,N'-bis(beta-chloroethyl)piperazinium dichloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   43,171,1952
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB158-507
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 55 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 167,334,1967
 
                            *** END OF RECORD ***