*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TM3404000 CHEMICAL NAME : Piperazinium, 1,1,4,4-tetramethyl-, dibromide CAS REGISTRY NUMBER : 24996-75-6 LAST UPDATED : 199106 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C8-H20-N2.2Br MOLECULAR WEIGHT : 304.12 WISWESSER LINE NOTATION : T6K DKTJ A1 A1 D1 D1 &E 2 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 93 HC * 1,1,4,4-Tetramethylpiperazinium dibromide *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4013507 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4013507 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1200 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - other changes REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 9,314,1954 *** END OF RECORD ***