*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : TM3546700
CHEMICAL NAME : 1-Piperidineacetic acid,
3-ethenyldodecahydro-1-oxo-3,4a,7,7,10a-pentamethyl-5
,10,10b- trihydroxy-1H-naphtho(2,1-b)pyran-6-yl
ester, hydrochloride, hydrate, (3R-(3-alpha,4a-
beta,5-beta,6-beta,6a-alpha,10-alpha,10a-beta,10b-alp
ha))-
CAS REGISTRY NUMBER : 114376-11-3
LAST UPDATED : 199409
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C27-H43-N-O7.Cl-H.H2-O
MOLECULAR WEIGHT : 548.19
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 8,13-Epoxy-6-beta-(piperidinoacetoxy)-1-alpha,7-beta,9-alpha-trihydroxy-
labd-14-en-11-one HCl
* HL 706
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 230 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 43,313,1993
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 85 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 31,1872,1988
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 73 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 43,313,1993
*** END OF RECORD ***