*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM3720000
CHEMICAL NAME           : 2-Piperidineacetic acid, alpha-phenyl-, methyl ester,
                          threo-
CAS REGISTRY NUMBER     : 52760-39-1
LAST UPDATED            : 198207
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H19-N-O2
MOLECULAR WEIGHT        : 233.34
WISWESSER LINE NOTATION : T6NTJ AYR&VO1  -THREO
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * threo-Methylphenydate
   * alpha-Phenyl-2-piperidineacetic acid methyl ester (threo isomer)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 39 mg/kg
TOXIC EFFECTS :
   Behavioral - wakefulness
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   8,263,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 39 mg/kg
TOXIC EFFECTS :
   Behavioral - wakefulness
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   8,263,1961
 
                            *** END OF RECORD ***