*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM4166500
CHEMICAL NAME           : Piperidine,
                          1-(1-amino-2-(benzyl(2,6-dimethyl-4-pyridyl)amino)eth
                          yl)-, dihydrobromide
LAST UPDATED            : 198803
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H30-N4.2Br-H
MOLECULAR WEIGHT        : 500.39
SYNONYMS/TRADE NAMES :
   * 1-(1-Amino-2-(benzyl(2,6-dimethyl-4-pyridyl)amino)ethyl)piperidine  
   dihydrobromide
   * N-Benzyl-N-(4-(2,6-lutidyl))-beta-(1-piperidyl)-ethylenediamine  
   dihydrobromide
   * Neo-restamin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   53,375,1957
 
                            *** END OF RECORD ***