*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM4375000
CHEMICAL NAME           : Piperidine, 2-benzhydryl-3-hydroxy-N-methyl-,
                          hydrochloride
CAS REGISTRY NUMBER     : 19974-69-7
LAST UPDATED            : 199803
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C19-H23-N-O.Cl-H
MOLECULAR WEIGHT        : 317.89
WISWESSER LINE NOTATION : T6NTJ A1 BYR&R CQ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Benzhydryl-3-hydroxy-N-methylpiperidine hydrochloride
   * 2-(Diphenylmethyl)-1-methyl-3-piperidinol hydrochloride
   * 3-Piperidinol, 2-(diphenylmethyl)-1-methyl-, hydrochloride
   * Sch 5472
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,301,1972
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 34 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 11,792,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 4 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,301,1972
 
                            *** END OF RECORD ***