*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM4733270
CHEMICAL NAME           : Piperidine,
                          1-(2-(benzyl(2,6-dimethyl-4-pyridyl)amino)ethyl)-,
                          dihydrobromide, hydrate
LAST UPDATED            : 198812
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H29-N3.2H-Br.H2-O
MOLECULAR WEIGHT        : 423.48
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-Benzyl-N-(4-(2,6-dimethylpyridyl))-p-(1-piperidyl)ethylamine  
   dihydrobromide hydrate
   * 2,6-Lutidine, 4-(benzyl(2-piperidinoethyl)amino)-, dihydrobromide,  
   monohydrate
   * Neo-restamine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 244 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Skin and Appendages - hair
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   54,33,1958
 
                            *** END OF RECORD ***