*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM5047000
CHEMICAL NAME           : Piperidine, 4-tert-butyl-1-nitroso
CAS REGISTRY NUMBER     : 46061-25-0
OTHER CAS REGISTRY NOS. : 17721-94-7
BEILSTEIN REFERENCE NO. : 1342194
REFERENCE               : 5-20-04-00234 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H18-N2-O
MOLECULAR WEIGHT        : 170.29
WISWESSER LINE NOTATION : T6NTJ ANO DX1&1&1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 4-tert-Butyl-1-nitrosopiperidine
   * 4-(1,1-Dimethylethyl)-1-nitrosopiperidine
   * N-Nitroso-4-tert-butylpiperidine
   * Piperidine, 4-(1,1-dimethylethyl)-1-nitroso-
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4500 mg/kg/2Y-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Liver - tumors
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 2,1045,1981
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 250 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 111,135,1983
 
                            *** END OF RECORD ***