*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TM5979000
CHEMICAL NAME           : 1-Piperidinecarboxamide,
                          2,6-bis(p-methoxyphenyl)-N-ethyl-3-methyl-4-oxo-
CAS REGISTRY NUMBER     : 101997-62-0
LAST UPDATED            : 199309
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C23-H28-N2-O4
MOLECULAR WEIGHT        : 396.53
WISWESSER LINE NOTATION : T6N DVTJ AVM2 BR DO1& C1 FR DO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2,6-Bis(p-methoxyphenyl)-N-ethyl-3-methyl-4-oxo-1-piperidinecarboxamide
   * ITA 473
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Autonomic Nervous System - smooth muscle relaxant (mechanism undefined,
   spasmolytic)
   Behavioral - muscle weakness
   Behavioral - antianxiety
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 17,187,1982
 
                            *** END OF RECORD ***